Wellbutrin works by increasing available dopamine and norepinephrine, while Zoloft increases available serotonin. While both drugs work to treat depression, they do so by acting on different neurotransmitters which affect mood.

What's better Zoloft or Wellbutrin?

Zoloft (sertraline) is good for treating depression and anxiety, but it can interact with many medicines. Improves mood. Wellbutrin (Bupropion) is good for treating depression and has fewer sexual side effects than other antidepressants, but you need to be okay with avoiding alcohol.

Can you take Zoloft and Wellbutrin together?

Talk to your doctor before using buPROPion together with sertraline. Combining these medications may increase the risk of seizures, which may occur rarely with either medication. In addition, buPROPion can increase the blood levels of sertraline, which may increase other side effects.

Does Wellbutrin give you energy?

On the other hand, bupropion does stand out among the antidepressants as having a positive effect on energy. When patients are up and active during the day, they are likely to sleep better at night.

Is there a better antidepressant than Zoloft?

Vital Information: In a study on patients who suffer from major depression, the drug Effexor was more likely than Prozac or Zoloft to result in full recovery. Researchers suspect Effexor is more effective because it acts on two different brain chemicals that transmit messages and are thought to control mood.

Does Wellbutrin make you hornier?

"It's definitely the antidepressant that we know does not have adverse sexual side effects," Friedman says. "It works in a different way than common SSRIs like Prozac and Paxil. Instead it increases norepinephrine and dopamine," which are involved in female sexual response.

Does Wellbutrin make you hypersexual?

After all, since when is an orgasm a cause for alarm? I was worried, though, that the addition of Wellbutrin had set off an episode of mania, an effect that antidepressants can have in up to 5 percent of patients. In that case, her prolonged orgasm might be a symptom of hypersexuality, common in mania.

What is the most energizing antidepressant?

Prozac (fluoxetine) and Wellbutrin (bupropion) are examples of “energizing” antidepressants; whereas Paxil (paroxetine) and Celexa (citalopram) tend to be more sedating.

Does Wellbutrin calm you down?

One case study found that bupropion at a dose of 150 milligrams daily improved panic and anxiety symptoms in an individual with panic disorder. Anecdotal evidence also supports the use of bupropion in addition to other medications to treat panic disorder.

What antidepressant helps you lose weight?

"In conclusion, we find that bupropion is the only antidepressant associated with long-term weight loss (although this effect is limited to nonsmokers)."

Does Wellbutrin help with motivation?

In summary, bupropion can increase the motivation to work for food reinforcement, particularly in animals with poor baseline performance.

Does Wellbutrin make you happy?

For the most part, Wellbutrin is considered to be a relatively safe antidepressant. However, since Wellbutrin affects the “feel-good” brain neurotransmitters norepinephrine and dopamine, it is sometimes taken to achieve a stimulant-like high.

Will I lose weight on Wellbutrin?

However, one antidepressant, bupropion (also known as Wellbutrin) seems to have the opposite effect. Weight is often lost while on the drug, and gained after it is stopped. Bupropion is a medication prescribed for depression, but also as an aid to smoking cessation.

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