Difference Between Sentinel and Axillary Lymph Nodes

April 2023 · 4 minute read

Axillary dissection removes more nodes and disrupts more of the normal tissue in the underarm area than a sentinel node biopsy. So, it's more likely to affect arm function and more likely to cause lymphedema. For this reason, sentinel node biopsy is the preferred method to check the axillary lymph nodes.

Is sentinel node the same as axillary node?

Surgically removing those lymph nodes is called axillary lymph node dissection. When early-stage breast cancer is removed, the lymph node or nodes closest to the cancer -- called the sentinel node(s) -- often is removed and sent to a pathologist for evaluation.

Are sentinel nodes axillary nodes?

The sentinel lymph node (SLN) is the underarm (axillary) lymph node closest to a breast cancer. During surgery to remove early-stage breast cancer, the sentinel node often is removed and sent to a pathologist who determines if there is cancer in it.

How many sentinel lymph nodes are there?

The surgeon then removes the sentinel nodes. In most cases, there are one to five sentinel nodes, and all are removed. The sentinel nodes are sent to a pathologist to examine under a microscope for signs of cancer. In some cases, sentinel node biopsy is done at the same time as surgery to remove the cancer.

What does the sentinel lymph node do?

Sentinel lymph nodes are an important part of the immune system, and they contain the cells that monitor foreign substances, like bacteria, viruses and cancer. Sentinel lymph node mapping helps to identify the lymph nodes that are at highest risk for containing cancer.

What happens if sentinel node is positive?

If the biopsy is positive, it means that cancer cells have been found in the sentinel lymph node. The surgeon may then proceed with axillary lymph node dissection—a more invasive procedure that involves removing more lymph nodes. For certain types of cancer, biopsy results are also used to determine the cancer stage.

How painful is a sentinel node biopsy?

After a sentinel node biopsy, many people have no side effects. Some people have pain or bruising at the cut (incision) and feel tired. Your breast and underarm area may be slightly swollen. This may last a few days.

What happens when axillary lymph nodes are removed?

When lymph nodes are removed, the liquid they store (lymph) can begin to collect in the area. More lymph nodes are removed with ALND, which raises the risk of lymphedema. Patients with lymphedema are more likely to have an infection in the affected arm. Patients must carefully watch for swelling or changes.

What is normal size of axillary lymph nodes?

The normal axillary lymph node should be oval and should have a smooth, well-defined margin (Fig 16). The cortex should be slightly hypoechoic and uniformly thin, measuring 3 mm or less. Nodes that meet this description have a very high negative predictive value for excluding metastases (9,18).

Does mammogram show axillary lymph nodes?

Axillary lymph nodes are often seen on MLO mammograms. Abnormal axillary lymph nodes are predominantly due to nonspecific reactive hyperplasia, followed by metastases from primary breast malignancy; however, there are a number of systemic processes that can also cause axillary lymphadenopathy.

How many lymph nodes are under your armpit?

The body has about 20 to 40 bean-shaped axillary lymph nodes located in the underarm area. These lymph nodes are responsible for draining lymph – a clear or white fluid made up of white blood cells – from the breasts and surrounding areas, including the neck, the upper arms, and the underarm area.

Do lymph nodes grow back after surgery?

As the lymphatic system is regenerated and returns to normal activity, patients start seeing the fluid volumes in the limb decrease and the lymphedema becomes easier for them to manage. It can take up to a year for complete healing after lymph node transfer surgery.

How long does a sentinel node biopsy take?

The radiographer marks where these nodes are on your skin. The scan takes about 90 minutes or more, depending on where the melanoma is and where the sentinel nodes are.

ncG1vNJzZmidnmOxqrLFnqmbnaSssqa6jZympmeRp8Gqr8ueZp2hlpuys7HNnJyYmpWpxKaxzZiqnqaknrumuL6apZ2Xka22rbjAq7CYpKmivamrzaibnqs%3D